Can I take Collagen and Omeprazole together?

You can generally take collagen and omeprazole together but it is recommended that you take them at different times.

It is usually best to take your omeprazole first thing in the morning on an empty stomach (as prescribed) and take your collagen supplement at a different time of day, such as with a meal later in the afternoon, to give your body the best chance of absorbing it.

Why this happens

Collagen is a protein that needs stomach acid to be broken down into smaller pieces (amino acids) so your body can absorb it. Omeprazole works by reducing the amount of acid your stomach produces. With less acid available, your body may find it harder to fully digest and absorb the collagen supplement.

You may be experiencing an interaction between collagen and omeprazole if:

• You notice reduced benefit from the collagen supplement, such as no improvement in skin, hair, or joint symptoms.

• You develop new or worsening digestive symptoms, including bloating, nausea, or indigestion.

• You experience changes in bowel habits, such as diarrhoea or constipation.

• You feel unusually tired, which may be linked to reduced nutrient absorption.

• Blood tests show low levels of certain nutrients, such as vitamin B12 or iron.
  

If you have any of the above symptoms, you should:

• Speak to your GP or pharmacist for personalised advice.

• Do not stop taking omeprazole suddenly unless advised by a healthcare professional.

• Consider reviewing your supplement use, including the dose and timing of collagen.

• Seek medical advice if digestive symptoms persist or worsen.

• Attend any blood tests arranged to check for nutrient deficiencies.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.