Can I take Cordyceps and Turkey tail together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known negative interactions between cordyceps and turkey tail mushrooms. In fact, they are often taken together in 'mushroom blends' because they work in similar ways to support the immune system. However, because both can stimulate the immune system, there is a theoretical risk for people with certain health conditions.
In this article:
Why this happens
Both cordyceps and turkey tail contain compounds called polysaccharides (specifically beta-glucans) that interact with immune cells. Taking them together may have an additive effect on immune activity. There is no evidence that they interfere with how the body absorbs or breaks down one another.
What you should do
Back to contentsIt is generally safe to take these together. However, you should consult a doctor before use if you have an autoimmune disease (like lupus or rheumatoid arthritis) or if you are taking immunosuppressant medications, as these supplements might make those conditions worse or interfere with your medicine. Stop taking both at least two weeks before any scheduled surgery as they may affect blood clotting.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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