Can I take Atorvastatin and Biotin together?

Why this happens

Atorvastatin is processed by specific liver enzymes (CYP3A4), while biotin (Vitamin B7) is a water-soluble vitamin that uses different pathways for absorption and processing. They do not interfere with each other's levels or effects in the body.

You can continue taking both as prescribed or recommended. However, always inform your doctor or pharmacist about all supplements you are taking, as biotin can sometimes interfere with the accuracy of certain blood tests (such as thyroid or heart enzyme tests).

Pregnancy

You must not take atorvastatin if you are pregnant or trying to become pregnant, as it may harm the unborn baby. Use effective contraception while taking this medicine.

Muscle pain or weakness - atorvastatin

Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness. In rare cases, this can lead to serious kidney problems.

Laboratory blood tests

Biotin can significantly interfere with certain lab tests, including heart attack markers (troponin) and thyroid tests, leading to incorrect results. Stop taking biotin at least 72 hours before any blood tests.

Grapefruit juice

Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This can increase your risk of side effects, such as muscle pain or damage. You should avoid drinking large amounts (more than 1.2 litres daily) of grapefruit juice, though a small glass occasionally is usually safe.

Alcohol

While there is no direct interaction, drinking large amounts of alcohol while taking atorvastatin can increase your risk of liver problems. It is best to stay within the recommended low-risk guidelines (no more than 14 units per week).

Raw egg whites

Eating large amounts of raw egg whites over a long period can prevent your body from absorbing biotin. This is because raw egg whites contain a protein called avidin that binds to biotin. Cooked eggs do not cause this issue.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.