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Can I take 2.5 and Quercetin together?

Drug interaction guide

Quercetin may increase the levels of apixaban (Eliquis) in your blood. This can make your blood too thin and significantly increase your risk of serious bleeding, such as bruising easily, nosebleeds, or internal bleeding.

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Why this happens

Apixaban is cleared from the body by a protein called P-glycoprotein (P-gp) and an enzyme called CYP3A4. Quercetin can block both of these, which stops the body from breaking down the medication properly, leading to a buildup of the drug.

You should avoid taking quercetin supplements while taking apixaban. If you are already taking both, speak to your doctor or pharmacist before stopping or changing your dose. Seek immediate medical help if you notice signs of bleeding, such as blood in your urine, black tarry stools, or coughing up blood.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 12 May 2026 | Originally published
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