Can I take 2.5mg and Omega together?
Drug interaction guide
Originally published 12 May 2026
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Taking omega-3 fatty acids (fish oil) alongside blood-thinning medications like apixaban can increase the risk of bruising or bleeding. While the risk is generally low at standard doses, both substances affect how your blood clots.
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Why this happens
Apixaban is an anticoagulant that prevents blood clots by blocking a specific protein (Factor Xa). Omega-3 fatty acids have a mild 'antiplatelet' effect, meaning they make the small cells in your blood (platelets) less sticky. When used together, their combined effects can make it harder for your blood to clot if you are injured.
What you should do
Back to contentsYou should inform your doctor or pharmacist if you plan to take omega-3 supplements with apixaban. Watch for signs of unusual bleeding, such as frequent nosebleeds, bleeding gums when brushing teeth, or large bruises that appear for no reason. If you have a fall or a head injury, seek medical advice immediately. Do not exceed the recommended dose of fish oil.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published
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