Can I take Amitriptyline and Glucosamine together?

Why this happens

The exact way these two interact is not fully understood, but it is thought that glucosamine may interfere with the enzymes in the liver that break down amitriptyline, leading to higher levels of the medicine in your bloodstream.

It is generally safe to take these together, but you should monitor yourself for any new or worsening side effects. If you feel unusually sleepy, dizzy, or notice a very dry mouth, speak to your pharmacist or GP. If you also take blood thinners (like warfarin), you must inform your doctor before starting glucosamine.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.