Can I take Amlodipine and Betahistine dihydrochloride together?
Drug interaction guide
Originally published 12 May 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
There is no known direct interaction between amlodipine and betahistine. However, both medications can affect your blood pressure. Amlodipine is designed to lower blood pressure, while betahistine can occasionally cause a slight drop in blood pressure as a side effect. Taking them together might lead to feeling a bit dizzy or lightheaded, especially when standing up quickly.
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
Amlodipine is a calcium channel blocker that relaxes blood vessels to lower blood pressure. Betahistine is a histamine analogue used for balance disorders; while it primarily works on the inner ear, it can have minor vasodilating (vessel-widening) effects elsewhere in the body. This could theoretically lead to an additive effect on lowering blood pressure.
What you should do
Back to contentsIt is generally safe to take these two medicines together. When starting betahistine or changing your dose, monitor how you feel. If you feel dizzy, lightheaded, or faint, sit or lie down until the feeling passes. Move slowly when changing positions (like getting out of bed). If these symptoms persist, mention it to your doctor or pharmacist.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Drug interactions checker
Can I take Aspirin and Furosemide together?
Taking aspirin and furosemide together can make the furosemide (water tablet) less effective at removing excess fluid from your body. Additionally, at high doses of aspirin, there is an increased risk of kidney problems and a build-up of aspirin in your blood, which can lead to side effects like ringing in the ears (tinnitus).

Drug interactions checker
Can I take Alcohol and Rosuvastatin together?
Drinking alcohol while taking rosuvastatin can increase the risk of liver problems and a rare but serious muscle condition called rhabdomyolysis. While a small amount of alcohol is usually fine, heavy or regular drinking makes side effects much more likely.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.