Can I take Apixaban and Fibre supplements together?

Why this happens

Fibre supplements (like psyllium husk or methylcellulose) work by absorbing water and forming a gel-like substance in the gut. This bulk can trap medication molecules or speed up their passage through the digestive system, reducing the time the body has to absorb the drug into the bloodstream.

To be safe, take your apixaban at least 2 hours before or 2 hours after taking a fibre supplement. This gap ensures the fibre does not interfere with the absorption of your medication. Do not stop taking your prescribed medication without speaking to your doctor or pharmacist.

Bleeding risk and surgery

You must tell your doctor or dentist you are taking apixaban before any surgery or dental procedure, as it may need to be stopped temporarily to prevent dangerous bleeding.

Drug absorption and timing

Fibre supplements can prevent other medicines from being absorbed properly. Take apixaban at least 2 hours before or after taking a fibre supplement to ensure your blood thinner remains effective.

Intestinal blockage

You must drink plenty of water (at least 200ml) with every dose of fibre. Without enough fluid, the supplement can swell and cause a blockage in your throat or intestine.

Water and non-alcoholic fluids

You must drink plenty of water (at least 200ml per dose) when taking fibre supplements. If you do not drink enough fluid, the supplement can swell and cause a blockage in your throat or gut.

Alcohol

While there is no direct interaction between apixaban and alcohol, drinking heavily increases your risk of stomach bleeding and falls, which can be more dangerous while taking a blood thinner. It is best to stick to moderate drinking limits.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.