Can I take Ashwagandha and Vitamin B2 together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known significant interactions between ashwagandha and vitamin B2 (riboflavin). They are generally considered safe to take together.
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Why this happens
Ashwagandha is an adaptogenic herb that primarily affects the body's stress response system, while vitamin B2 is a water-soluble vitamin essential for energy production. They do not share the same metabolic pathways in the liver, nor do they have opposing or overlapping effects that would cause a safety concern.
What you should do
Back to contentsYou can take these two supplements together. As with any supplement, it is best to follow the dosage instructions on the product labels and inform your doctor or pharmacist about everything you are taking.
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Important precautions
Back to contentsPregnancy
Do not use ashwagandha during pregnancy as it may have abortifacient effects (it could cause a miscarriage).
Autoimmune diseases (e.g., Lupus, Rheumatoid Arthritis, Multiple Sclerosis)
Ashwagandha can stimulate the immune system, which may worsen the symptoms of autoimmune conditions.
Hyperthyroidism (overactive thyroid)
Ashwagandha can increase thyroid hormone levels. You must avoid it if you have an overactive thyroid, as it may worsen your condition or interfere with thyroid medications.
Scheduled Surgery
Stop taking ashwagandha at least 2 weeks before surgery; it can slow down the central nervous system and may dangerously increase the effect of anaesthesia.
Food and drink warnings
Back to contentsAlcohol
Ashwagandha has sedative properties and may enhance the effects of alcohol. Combining them can lead to excessive drowsiness, impaired coordination, and slowed reaction times. It is best to avoid or strictly limit alcohol while taking this supplement.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Treatment and medication
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Taking black cohosh and solifenacin together may increase the risk of side effects such as a dry mouth, blurred vision, constipation, or feeling overheated. There is also a small possibility that black cohosh could affect how your liver breaks down solifenacin, potentially leading to higher levels of the medicine in your body.
Treatment and medication
Can I take Calcium and Ezetimibe together?
There is no known interaction between calcium supplements and ezetimibe. Taking these two together is generally considered safe and should not affect how well your cholesterol medication works.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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