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Can I take Asprin and Hydroxycarbamide together?

Drug interaction guide

Taking aspirin and hydroxycarbamide together can increase your risk of bleeding and may cause your blood cell counts to drop lower than intended.

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Why this happens

Both medications can lower the number of platelets in your blood (the cells that help your blood clot). Aspirin also makes the remaining platelets less 'sticky'. Additionally, hydroxycarbamide can cause your bone marrow to produce fewer blood cells, which can lead to a higher risk of bruising or bleeding when combined with aspirin's blood-thinning effects.

You should only take these two medications together if they have been specifically prescribed by your doctor, as they are sometimes used together under strict supervision for certain blood conditions. You must have regular blood tests as requested by your medical team. Seek immediate medical advice if you notice unusual bruising, small red spots on the skin, nosebleeds, or blood in your urine or stools.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 12 May 2026 | Originally published
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