Can I take Atorvastatin and Co-codamol together?
Drug interaction guide
Originally published 12 May 2026
Meets Patient’s editorial guidelines
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There is no known direct interaction between atorvastatin and co-codamol. It is generally safe to take these two medications together.
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Why this happens
Atorvastatin is a cholesterol-lowering medicine (statin) processed mainly by a specific liver enzyme (CYP3A4). Co-codamol is a combination of paracetamol and codeine. Paracetamol and codeine are processed by different pathways in the liver and do not interfere with how atorvastatin works or how it is cleared from the body.
What you should do
Back to contentsYou can take these medicines together as prescribed. However, always be mindful of the side effects of each. If you experience unusual muscle pain, tenderness, or weakness (potential side effects of atorvastatin) or extreme drowsiness and constipation (potential side effects of co-codamol), speak to your doctor or pharmacist.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published
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