Can I take Collagen and Tamoxifen together?

Why this happens

Collagen is broken down into amino acids in the digestive tract, similar to eating protein-rich food. It does not interfere with the liver enzymes (such as CYP2D6) that tamoxifen relies on to work, nor does it have known oestrogen-like effects that would interfere with tamoxifen's purpose.

You can safely take collagen supplements with tamoxifen. However, always choose high-quality supplements from reputable brands to ensure there are no hidden additives or contaminants. If you have any concerns about new supplements, it is always a good idea to mention them to your oncology team.

Grapefruit and grapefruit juice

Grapefruit contains compounds that can interfere with the enzymes (specifically CYP3A4) that process tamoxifen in your body. This may potentially alter how much of the medicine stays in your bloodstream, although the clinical impact is less severe than with other medications. It is generally advised to avoid large amounts of grapefruit.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.