Can I take Diazepam and Morphine together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking diazepam and morphine together can cause extreme sleepiness, very slow or shallow breathing, and difficulty staying awake. In severe cases, this combination can lead to a coma or be life-threatening.
In this article:
Why this happens
Both drugs are 'central nervous system depressants'. This means they both slow down brain activity and the signals that tell your body to breathe. When taken together, their effects add up, making the sedation and breathing problems much stronger than if either drug were taken alone.
What you should do
Back to contentsYou should only take these two medicines together if they have been specifically prescribed by the same doctor who is aware you are taking both. If you must take both, use the lowest dose possible for the shortest time. Seek emergency medical help immediately if you experience extreme dizziness, fainting, very slow breathing, or if you cannot stay awake. Avoid alcohol and do not drive or operate machinery while taking this combination.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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