Can I take Evening primrose oil and Vitamin c together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known significant interactions between evening primrose oil and vitamin C. It is generally considered safe to take these two supplements together.
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Why this happens
Evening primrose oil is a source of omega-6 fatty acids (specifically gamma-linolenic acid), while vitamin C is a water-soluble antioxidant. They are processed by the body through different pathways and do not interfere with each other's absorption, metabolism, or effectiveness. In fact, some evidence suggests that antioxidants like vitamin C may help protect the fatty acids in evening primrose oil from oxidising (breaking down) in the body.
What you should do
Back to contentsYou can continue to take both supplements as directed. As with any supplement, it is best to take them with food to reduce the chance of an upset stomach. If you have any underlying health conditions or are taking prescribed medications (especially blood thinners or epilepsy medication), consult your pharmacist or doctor before starting new supplements.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Treatment and medication
Can I take Black garlic and Evening primrose oil together?
Taking black garlic and evening primrose oil together may increase your risk of bruising or bleeding. This is because both supplements can thin the blood and slow down the time it takes for a clot to form.

Treatment and medication
Can I take Dextromethorphan cough medicines and Sertraline together?
Taking these two medicines together can increase the risk of a rare but serious condition called 'serotonin syndrome'. This happens when there is too much of a chemical called serotonin in your brain. Symptoms can include feeling very agitated, confused, shaky, sweaty, or having a fast heartbeat and muscle twitches. Additionally, the cough medicine may make you feel more drowsy or dizzy than usual.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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