Can I take Fluanxol and Pregabalin together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
Taking Fluanxol (flupentixol) and pregabalin together can make you feel very sleepy, dizzy, and unsteady on your feet. It may also slow down your breathing and affect your coordination or concentration.
In this article:
Video picks for Drug interactions
Why this happens
Both medicines work by slowing down activity in the central nervous system (the brain and nerves). When used together, their sedative effects are added together (an additive effect), making the side effects much stronger than if you took either medicine alone.
What you should do
Back to contentsUse this combination with caution. Avoid driving, operating heavy machinery, or performing tasks that require you to be alert until you know how these medicines affect you. Do not drink alcohol while taking these medicines, as it will make the sleepiness much worse. If you feel extremely drowsy or have difficulty breathing, contact your doctor immediately.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Calcium and Doxycycline together?
Taking calcium at the same time as doxycycline can stop the antibiotic from working properly. The calcium attaches to the medicine in your stomach, which prevents your body from absorbing it into your bloodstream. This means the infection you are treating might not clear up as it should.

Treatment and medication
Can I take Black cohosh and Vitamin C together?
There are no known significant interactions between black cohosh and vitamin C. It is generally considered safe to take these two supplements together.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.