Can I take Gabapentin and Ibuprofen together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There is no known direct interaction between gabapentin and ibuprofen. It is generally considered safe to take these two medicines together.
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Why this happens
Gabapentin and ibuprofen work in different ways and are processed by different organs in the body. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation, while gabapentin targets nerve signals. They do not interfere with each other's absorption or metabolism.
What you should do
Back to contentsYou can take these medicines together if both have been recommended for you. However, both can occasionally cause side effects like dizziness or drowsiness. If you feel particularly sleepy or unsteady when taking them together, avoid driving or using tools and speak to your pharmacist or doctor. Always take ibuprofen with food to protect your stomach.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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