Can I take Iu and Amlodipine together?
Drug interaction guide
Originally published 12 May 2026
Meets Patient’s editorial guidelines
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There is no known interaction between ibuprofen and amlodipine. However, ibuprofen can sometimes make blood pressure medications less effective if taken regularly over a long period.
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Why this happens
Ibuprofen belongs to a group of medicines called NSAIDs. These can cause the body to hold onto salt and water, which may slightly increase blood pressure, potentially working against the effects of amlodipine.
What you should do
Back to contentsIt is generally safe to take these together for short-term pain relief (a few days). If you need to take ibuprofen for a long time, you should have your blood pressure checked regularly by your doctor or pharmacist.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published

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