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Can I take Lamotrigine and Ramipril together?

Drug interaction guide

There are no known significant interactions between lamotrigine and ramipril. It is generally considered safe to take these two medications together.

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Why this happens

Lamotrigine and ramipril are processed by the body using different pathways. Lamotrigine is primarily broken down by the liver through a process called glucuronidation, while ramipril is processed by different liver enzymes and cleared by the kidneys. They do not interfere with each other's absorption or excretion, nor do they have overlapping side effects that would cause concern.

You can continue taking both medications as prescribed by your doctor. As with any new medication, monitor how you feel and report any unusual symptoms to your GP or pharmacist. Always ensure your healthcare provider is aware of all the medicines you are taking.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 12 May 2026 | Originally published
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