Can I take Losec and Turmeric together?
Drug interaction guide
Originally published 12 May 2026
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Taking turmeric alongside Losec (omeprazole) may increase the amount of the medicine that stays in your bloodstream. It might also make the medicine less effective at reducing stomach acid for some people.
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Why this happens
Turmeric contains a compound called curcumin. Curcumin can interfere with the natural enzymes in your liver (specifically CYP2C19 and CYP3A4) that break down Losec. This can lead to higher levels of the medicine in your body. Additionally, while turmeric is often used for digestion, it can sometimes stimulate the production of stomach acid, which works against what Losec is trying to achieve.
What you should do
Back to contentsIt is generally fine to use turmeric in normal cooking amounts. However, if you are taking high-dose turmeric or curcumin supplements, you should speak with your doctor or pharmacist first. Monitor yourself for any new side effects or if your acid reflux symptoms seem to get worse.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published

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