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Can I take Magnesium and Milk thistle together?

Drug interaction guide

There are no known significant interactions between magnesium supplements and milk thistle (silymarin). Both are generally considered safe to take together.

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Why this happens

Magnesium and milk thistle do not share the same metabolic pathways in the liver, nor do they interfere with each other's absorption in the digestive tract. They also have different primary effects on the body.

You can safely take these two supplements together. As with all supplements, it is best to follow the dosage instructions on the packaging and inform your GP or pharmacist about everything you are taking.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 12 May 2026 | Originally published
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