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Can I take Furosemide and Lansoprazole together?

Drug interaction guide

Taking these two medicines together can lead to low levels of magnesium in your blood. It may also increase the risk of low potassium or sodium levels. Low magnesium can cause symptoms like tiredness, muscle cramps, or an irregular heartbeat.

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Why this happens

Furosemide is a 'water tablet' that makes the kidneys flush out minerals like magnesium and potassium. Lansoprazole reduces stomach acid, which can sometimes interfere with how the body absorbs magnesium from food. When used together, they both deplete your mineral stores through different pathways.

You can take these medicines together, but your doctor may want to perform regular blood tests to check your mineral levels (especially magnesium and potassium). If you experience unusual muscle weakness, spasms, or a racing heart, contact your GP.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 12 May 2026 | Originally published
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